Desmoid Care Pathways

4. Desmoid Tumor Treatment - Medical therapy

1. Desmoid Risk Factor (DRF)

Risk score:

1. FH desmoids 0 (1 point) 1 (2 points) >1(3 points)

2. Gender F(3 points), M (1 point)

3. Extracolonic Manifestations (Gardner’s) 0(1 point), 1 (2 points), >1 (3 points)

4. Genotype 5’ of codon700 (1 point), 700-1399 2 points, 3’ of 1399 (3 points)

DRF is the total number of points, used to classify patients as follows:

• Low risk = 4-6

• Moderate risk = 7-9

• High risk = 10-12

2. Surgical Planning

3. Desmoid Tumor Treatment - Surgery